Zika Virus Net is the web resource for anyone interested in Zika virus. Zika virus (ZIKV) is an insect-borne virus, of the flavivirus genus, that is spread by Aedes mosquitoes. The most common symptoms of Zika virus disease (Zika) are fever, rash, joint pain, and red eye. The illness is usually mild with symptoms lasting from several days to a week. Severe disease requiring hospitalization is uncommon. The symptoms of Zika are similar to those of dengue and chikungunya, which are diseases caused by other viruses spread by the same type of mosquitoes. Zika virus can be spread from a pregnant woman to her unborn baby. There have been reports of a serious birth defect of the brain called microcephaly and other poor pregnancy outcomes in babies of mothers who were infected with Zika virus while pregnant. On February 1st, 2016, the WHO declared the Zika outbreak as a Public Health Emergency of International Concern (PHEIC). As of August 2017 the number of new Zika virus cases in the Americas had fallen dramatically.

The objectives of Zika Virus Net are to be the public and professional information resource for zika fever and to serve as a network in the exchange of information and news related to zika.

• Zika Virus: Cases Jump to 44 in Kerala; Here's All You Need to Know About the Disease | The Weather Channel - Articles from The Weather Channel | weather.com - The Weather Channel
  Fri, 23 Jul 2021 04:25 GMT
• Zika virus: Symptoms, prevention, history and treatment. Check all details - Mint
  Fri, 09 Jul 2021 07:00 GMT
• Mapping dengue hot spots pinpoints risks for Zika and chikungunya - Emory News Center
  Wed, 07 Jul 2021 07:00 GMT
• Zika Virus Detected in India's Kerala State - Voice of America
  Fri, 09 Jul 2021 07:00 GMT
• Kerala reports 5 new Zika virus cases, 7 active cases in state - Mint
  Thu, 29 Jul 2021 14:45 GMT
• Study refutes suspicion that dengue increases risk of microcephaly associated with zika - EurekAlert
  Tue, 20 Jul 2021 16:46 GMT
• Tied in knots: Zika virus tangles are the most stable RNA known - Nature.com
  Fri, 16 Jul 2021 07:00 GMT
• Five more test positive for Zika virus in Kerala - India Today
  Fri, 16 Jul 2021 07:00 GMT
• Five more Zika cases confirmed - The Hindu
  Thu, 29 Jul 2021 15:24 GMT
• Mosquito Prone To Carrying Zika Virus Identified In Wayne County - WKAR
  Thu, 15 Jul 2021 07:00 GMT
• Zika virus disease: 3 more test positive in Kerala as tally goes past 40, says health minister Veena George - Hindustan Times
  Wed, 21 Jul 2021 07:00 GMT
• Kerala reports two more cases of Zika virus, total tally now at 48 - Mint
  Sun, 25 Jul 2021 15:07 GMT
• Gennova to use mRNA tech to develop vaccines for Zika, tuberculosis - Business Standard
  Fri, 30 Jul 2021 00:32 GMT
• Risk Areas for Zika and Chikungunya Pinpointed by Mapping Dengue Hotspots - Technology Networks
  Thu, 08 Jul 2021 07:00 GMT
• Asian tiger mosquito, known to carry Zika virus, found in Michigan - WLNS
  Wed, 14 Jul 2021 07:00 GMT

• PRO/AH/EDR> Invasive mosquito - Canada: (ON)
  Wed, 07 Jul 2021 11:41:37 -0400
  Zika virus -- Canada
  Mosquito surveillance efforts in Windsor-Essex [Ontario, Canada] have detected a tropical invasive mosquito that can potentially spread the Zika virus.
  The mosquito, known as _Aedes albopictus_, was found within Windsor city limits, according to the Windsor-Essex County Health Unit [WECHU], which carries out mosquito surveillance.
  The mosquito is capable of transmitting the Zika virus, but it's not likely to be the main spreader of the infection, since it feeds on animals in addition to

• Zika virus isolation, propagation, and quantification using multiple methods Fri, 30 Jul 2021 06:00:00 -0400
  Zika virus (ZIKV) was isolated from the archival urine, serum, and autopsy specimens by intrathoracic inoculation of Toxorhynchitis splendens and followed by three blind sub-passaging in C6/36 mosquito cells. The virus isolates were identified using an immunofluorescence assay and real-time reverse transcription-polymerase chain reaction (real-time RT-PCR). This study analyzed 11 ZIKV isolates. One isolate (0.6%) was obtained from 171 urine samples, eight (8.7%) from 92 serum samples and two...
• Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques Fri, 30 Jul 2021 06:00:00 -0400
  Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance Zika virus (ZIKV) disease, due to the homology between ZIKV and DENV and the observation of antibody-dependent enhancement (ADE) among DENV serotypes. To date, no study has examined the impact of pre-existing DENV immunity on ZIKV pathogenesis during pregnancy in a translational non-human primate model. Here we show that macaques with a prior DENV-2 exposure had a higher burden of ZIKV vRNA in maternal-fetal...
• Social determinants associated with Zika virus infection in pregnant women Fri, 30 Jul 2021 06:00:00 -0400
  CONCLUSION: Eve after controlling for age, differences in key social determinants, as education and food security, were associated with the risk of ZIKV infection among pregnant women in Brazil. Our findings elucidate risk factors that can be targeted by future interventions to reduce the impact of ZIKV infection in this vulnerable population.
• Clinical phenotype in infants with negative Zika virus immunoglobulin M testing born to mothers with confirmed Zika virus infection during pregnancy Fri, 30 Jul 2021 06:00:00 -0400
  CONCLUSIONS: These data add support to previous reports of negative ZIKV IgM testing in infants with clear maternal and phenotypic evidence of congenital ZIKV infection. Follow-up care consistent with the diagnosis is recommended regardless of infant ZIKV test results.
• Detection of Zika virus in urine from randomly tested individuals in Mirassol, Brazil Fri, 30 Jul 2021 06:00:00 -0400
  CONCLUSION: Our study shows the effectiveness of urine as a non-invasive sample to detect the incidence of ZIKV infection. We also highlight the importance of ZIKV molecular diagnosis to aid public health surveillance and prevention of congenital Zika syndrome and other ZIKV-associated diseases.
• Maternal and neonatal outcomes related to Zika virus in pregnant women in Southern Vietnam: An epidemiological and virological prospective analysis Fri, 30 Jul 2021 06:00:00 -0400
  BACKGROUND: In 2016-2017, 68 women in Southern Vietnam had RT-PCR confirmed Zika virus (ZIKV) infection during pregnancy. We report here the outcomes of the pregnancies and the virological analyses related to this outbreak.
• The Ablation of Envelope Protein Glycosylation Enhances the Neurovirulence of ZIKV and Cell Apoptosis in Newborn Mice Fri, 30 Jul 2021 06:00:00 -0400
  Zika virus (ZIKV) has attracted the wide global attention due to its causal link to microcephaly. In this study, two amino acid (aa) mutation (E143K and R3394K) were identified at the fourth generation (named ZKC2P4) during the serial passage of ZIKV-Asian lineage ZKC2/2016 strain in the newborn mouse brain, while another seven aa deletions in envelope (E) protein were detected in ZKC2P6. ZKC2P6 is a novel nonglycosylated E protein Asian ZIKV we first identified and provides the first direct...
• Evaluation of bladder and bowel functions in children with microcephaly and congenital zika syndrome Fri, 30 Jul 2021 06:00:00 -0400
  CONCLUSION: Bladder and bowel dysfunction was confirmed in 80% of the children with CZS. This is a new Zika virus-associated neuromuscular disorder that needs to be further investigated.
• Phenotypical characterization of regulatory T cells in acute Zika infection Thu, 29 Jul 2021 06:00:00 -0400
  Zika virus (ZIKV), alongside Dengue virus (DENV), Chikungunya virus (CHIKV), and Yellow Fever Virus (YFV) are prevalent arboviruses in the Americas. Each of these infections is associated with the development of associated disease immunopathology. Immunopathological processes are an outcome of counter-balancing impacts between effector and regulatory immune mechanisms. In this context, regulatory T cells (Tregs) are key in modulating the immune response and, therefore, in tissue damage control....
• Persistence of aerially-sprayed naled in coastal sediments Thu, 29 Jul 2021 06:00:00 -0400
  Aerial sprays of the organophosphate pesticide, naled, were intensified over beach areas during the summer of 2016 to control the locally-acquired Zika outbreak in the continental U.S. Concerns were raised in beach frequented areas about contaminated sediments. The aim of this study was to evaluate the persistence and levels of naled and its byproduct, dichlorvos, in sediments obtained from the affected areas. Laboratory experiments were designed to simulate the effect of various natural...