Latest Articles on Zika Virus

  • Long-term consequences of sexually transmitted infections on men's sexual function: A systematic review Thu, 23 Sep 2021 06:00:00 -0400
    Objective: To systematically review the available literature on the long-term effects of sexually transmitted diseases (STIs) on male reproductive functions. Methods: A PubMed search was conducted on 3 January 2021, and as a result, 952 articles were retrieved. Exclusion of irrelevant articles resulted in 36 articles, dating from 1998 to 2020, which were analysed. Results: Only 52.8% of these articles described original research, while the rest were reviews. The majority (26) of the articles...
  • The Ability of Zika virus Intravenous Immunoglobulin to Protect From or Enhance Zika Virus Disease Thu, 23 Sep 2021 06:00:00 -0400
    The closely related flaviviruses, dengue and Zika, cause significant human disease throughout the world. While cross-reactive antibodies have been demonstrated to have the capacity to potentiate disease or mediate protection during flavivirus infection, the mechanisms responsible for this dichotomy are still poorly understood. To understand how the human polyclonal antibody response can protect against, and potentiate the disease in the context of dengue and Zika virus infection we used...
  • An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral Wed, 22 Sep 2021 06:00:00 -0400
    Galidesivir (BCX4430) is an adenosine nucleoside analog that is broadly active in cell culture against several RNA viruses of various families. This activity has also been shown in animal models of viral disease associated with Ebola, Marburg, yellow fever, Zika, and Rift Valley fever viruses. In many cases, the compound is more efficacious in animal models than cell culture activity would predict. Based on favorable data from in vivo animal studies, galidesivir has recently undergone evaluation...
  • A systematic evaluation of IgM and IgG antibody assay accuracy in diagnosing acute Zika Virus infection in Brazil; lessons relevant to emerging infections Wed, 22 Sep 2021 06:00:00 -0400
    Accurate diagnostics underpin effective public health responses to emerging viruses. For viruses, such as Zika virus (ZIKV), where the viremia clears quickly, antibody-based (IgM or IgG) diagnostics are recommended for patients who present seven days after symptom onset. However, cross-reactive antibody responses can complicate test interpretation among populations where closely related viruses circulate. We examined the accuracy (proportion of samples correctly categorized as Zika-positive or...
  • Antecedent infections in Guillain-Barré syndrome in endemic areas of arbovirus transmission: a multi-national case-control study Wed, 22 Sep 2021 06:00:00 -0400
    BACKGROUND AND AIMS: Half of the world's population is at risk of arthropod-borne virus (arbovirus) infections. Several arbovirus infections have been associated with Guillain-Barré syndrome (GBS). We investigated whether arboviruses are driving GBS beyond epidemic phases of transmission and studied the antibody response to glycolipids.
  • Zika virus amid COVID-19 in India: A rising concern Wed, 22 Sep 2021 06:00:00 -0400
    No abstract
  • The Suppressor of Cytokine Signalling family of proteins and their potential impact on COVID-19 disease progression Tue, 21 Sep 2021 06:00:00 -0400
    The family of Suppressor of Cytokine Signalling (SOCS) proteins plays pivotal roles in cytokine and immune regulation. Despite their key roles, little attention has been given to the SOCS family as compared to other feedback regulators. To date, SOCS proteins have been found to be exploited by viruses such as herpes simplex virus (HSV), hepatitis B virus (HBV), hepatitis C virus (HCV), Zika virus, respiratory syncytial virus (RSV), Ebola virus, influenza A virus (IAV) and SARS-CoV, just to name...
  • Application of Deep Learning to Community-Science-Based Mosquito Monitoring and Detection of Novel Species Tue, 21 Sep 2021 06:00:00 -0400
    Mosquito-borne diseases account for human morbidity and mortality worldwide, caused by the parasites (e.g., malaria) or viruses (e.g., dengue, Zika) transmitted through bites of infected female mosquitoes. Globally, billions of people are at risk of infection, imposing significant economic and public health burdens. As such, efficient methods to monitor mosquito populations and prevent the spread of these diseases are at a premium. One proposed technique is to apply acoustic monitoring to the...
  • Biochemical characterization of Aedes aegypti (Linnaeus) (Diptera: Culicidae) resistance to deltamethrin, fipronil, and imidacloprid Tue, 21 Sep 2021 06:00:00 -0400
    Aedes aegypti is an important vector of dengue fever, dengue hemorrhagic fever and yellow fever, chikungunya, and Zika virus. The objective was to evaluate the resistance of A. aegypti exposed to insecticides with different action modes (deltamethrin, imidacloprid, and fipronil) under intense selection pressure for 10 generations in laboratory. Bioassays were conducted according to World Health Organization. Biochemical assay performed after selection with deltamethrin (Delta-SEL), fipronil...
  • Host selection pattern and flavivirus screening of mosquitoes in a disturbed Colombian rainforest Tue, 21 Sep 2021 06:00:00 -0400
    Studies on the feeding behavior of hematophagous insects, particularly those of medical importance, are relevant for tracking possible pathogen transmission routes and identifying biases in the choice of vertebrates. We evaluated host selection of blood-feeding mosquitoes in a disturbed forest in the Magdalena Medio valley in Colombia from March 2017 to April 2018, after the introduction of Zika virus to the Americas from the 2015-2016 outbreak. We estimated vertebrate diversity and collected...

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